Black and white motion sensor camera capture of Sonoran Desert Toad staring into your soul at Organ Pipe Cactus National Monument, Arizona.

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Black and white motion sensor camera capture of Sonoran Desert Toad staring into your soul at Organ Pipe Cactus National Monument, Arizona. / National Park Service

Go into almost any park and there's often reminders to refrain from going near, petting or feeding wildlife. Not licking strange animals was simply a given — until now.

The National Park Service has added tongue-contact with the Sonoran desert toad among its various warnings for park visitors.

"As we say with most things you come across in a national park, whether it be a banana slug, unfamiliar mushroom, or a large toad with glowing eyes in the dead of night, please refrain from licking," the agency wrote on Facebook this past week.

The toad, also known as the Colorado river toad, is about seven inches in size and carries a weak, low-pitched ribbit sound. But the creature is far from harmless. Sonoran desert toads secrete a potent toxin that can make people sick if they touch it or get the poison in their mouth, according to the National Park Service.

Despite the risks, some people have discovered that the toad's toxic secretions contain a powerful hallucinogenic known as 5-MeO-DMT.

In recent years, smoking the amphibian's secretions has grown in popularity — so much so that the species is even considered threatened at least in New Mexico due to "collectors that want to use the animal for drug use," according to the state's Department of Game & Fish.

A number of public figures have reported experimenting with the toad's extracted toxins. Boxing legend Mike Tyson has spoken about it, and some researchers have even begun to study it for its potential therapeutic benefits. President Biden's son, Hunter Biden, has written about using 5-MeO-DMT therapy as a form of addiction treatment.

The U.S. Drug Enforcement Administration considers 5-MeO-DMT, as a Schedule 1 drug, meaning it is currently not accepted for medical use and has a high potential for abuse.

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