The Food and Drug Administration is working on a playbook for how it could greenlight vaccine tweaks. Studies in hundreds of people, rather than tens of thousands, seem likely.

Guidance from the CDC on who should be prioritized to get the COVID-19 vaccine was meant to be flexible and inclusive. But "the attempt to have equity created more inequity," says one researcher.

COVID-19 vaccines appear to work against the new coronavirus strains, though scientists are warily watching a variant first seen in South Africa. Vaccines may need updates to keep pace with the virus.

The Biden administration is promising 61 million rapid at-home tests by the summer. But critics say that's too few and way too late.

I haven't seen my mother in over a year. I was going to visit in April to celebrate her 90th birthday but the pandemic put that on hold. Now that she's been vaccinated is it time for the birthday hug?

This week’s Medical Minute, discusses a small group of neurons that are key players and logical treatment targets for a common mental health disorder.

This week’s Medical Minute, discusses efforts to improve vaccine efficacy using drugs, small molecules and gene editing technology.

The administration is in its early days, but the infectious disease expert says he's encouraged by the new president's attitude about the pandemic. Science, Fauci says, is "going to rule."

With vaccine still scarce, and eligibility differing from place to place, some people have easier access to "extra" doses than others. Careful, ethicists warn. Going out of turn is a slippery slope.

A new model estimates how many new infections are missed by testing and how many people are actively shedding the virus. The numbers are staggering and lend urgency to the vaccine race.

Supply shortages of oxygen for hospitals have plagued many countries, but the U.S. has averted the most dire — partly because the industry figured out new ways to share resources and anticipate needs.

The spread of new strains raises new questions as two COVID-19 vaccines continue their rollout across the U.S. and another vaccine candidate preps for regulatory review. Here's what you need to know.

The two companies producing COVID-19 vaccines for use in the United States will have to raise production to meet contractual goals of 100 million doses each by the end of March.

The Georgia governor's office says public health departments and other providers are being forced to “pause" appointments for people hoping to get vaccinated against the coronavirus in the Cobb-Douglas counties district.

Dr. Paul Stoffels, the chief scientific officer at Johnson & Johnson, tells NPR the company's vaccine is very effective where it matters most: preventing hospitalizations and deaths.