Updated COVID boosters are now available for anyone age 12 or older. The CDC is urging anyone who is eligible to sign up but some vaccine experts say some people might want to wait.

Two studies that have not yet been peer reviewed indicate increased protection against the infectious omicron variant.

Scientists are watching how Portugal and other highly vaccinated countries are faring against the coronavirus' new omicron variant.

If you were fully vaccinated more than six months ago, you may want to get a booster shot. That's a third dose of the Moderna and Pfizer mRNA vaccines or a second shot of the Johnson & Johnson brand.

Some experts worry "boostermania" is distracting from the goal of getting tens of millions of unvaccinated Americans their first shots.

Back in January, a handful of women founded the “Georgia COVID Appointment help” group on Facebook. Members and volunteers wanted to help those unfamiliar with technology get their shots. Now, they're navigating questions about booster shots and vaccine approval for children.

CDC Director Rochelle Walensky also endorsed a mix-and-match approach to boosters that would be flexible for patients and health care providers.

The Food and Drug Administration also gave an OK to boosters that differ from the vaccine originally used to immunize people against COVID-19. A mix-and-match approach could ease the booster rollout.

A panel of experts voted to recommend that the Food and Drug Administration authorize a booster dose of the Johnson & Johnson COVID vaccine at least two months after the first shot.

Johnson & Johnson has asked the Food and Drug Administration to authorize a booster for people 18 and older six months after initial immunization, with an option to vaccinate after two months.

With the back and forth on boosters from government agencies, many Americans are wondering if they really need an extra shot. Here is what the science says about who needs a booster now — and why.

Dr. Janet Woodcock, an administrative veteran of the Food and Drug Administration since the 1980s, has been acting director of the agency since January. Why is the permanent job so hard to fill?

Using the COVID vaccine "off-label" — whether that's for booster shots or young children — may be tempting to some vaccine providers, but the CDC warns it could get them into trouble.

The Pfizer mRNA vaccine is now not only safe and effective against COVID-19 serious illness and death: It’s also fully FDA approved. 

Dr. Cecil Bennett of Newnan says the most important thing is to listen to patients who have not yet been vaccinated and try to understand their concerns. 

Public health figures believe a focus on boosters for the already vaccinated will hasten the emergence of new variants among the billions of unvaccinated people — including a vaccine-resistant strain.