Monday marked Georgia’s rollout of the coronavirus vaccine to those over 65 and to first responders. The day saw a slew of logistical struggles across the state.

Some rural areas, where health care is usually harder to get, appear to be leading the nation in delivery of the COVID-19 vaccine. But health leaders are cautioning there are caveats.

In an NPR interview, Dr. Anthony Fauci, the country's top infectious disease expert, said changes in vaccine distribution could be necessary depending on what happens in the next few weeks.

The crisis starts around 2 a.m. at a hospital in Mendocino County, Calif. A compressor gives out, giving the staff two hours to use the coronavirus vaccines before they are declared unusable.

Cuomo says the patient is recovering. The governor also pledged not to receive the vaccine until Black, Hispanic and poor people do.

The British government has ordered 100 million doses, enough to vaccinate 50 million residents.

Even as the European Union began vaccine rollouts on Sunday, nations around the globe are instituting severe lockdowns and travel restrictions. Fear of the U.K. variant is a key reason.

Mathematical modeling suggests that the mutations in this variant make the virus more transmissible. What does that mean for preventive measures — and the new vaccines?

There's cause for concern. But how concerned should we be? Here's a rundown of the current thinking on key issues as transmission, severity of disease — and effectiveness of vaccines.

"Scientifically, it is highly likely that the immune response by this vaccine also can deal with the new virus variant," BioNTech CEO Ugur Sahin said Tuesday.

"Our war against the virus is not over yet, but this week we're taking a major step toward our eventual victory," Health and Human Services Secretary Alex Azar said.

Monday on Political Rewind: The first batch of COVID-19 vaccines is headed to hundreds of distribution centers in all 50 states.

A portion of the first coronavirus vaccines have been designated to go to Indian Country, but some tribes are skeptical about the federal government's ability to deliver and distribute the vaccines.

The Food and Drug Administration's authorization of a COVID-19 vaccine could come in a day or two, a member of an FDA expert panel says. But he says it may be late 2021 before normalcy returns.

False claims about COVID-19 vaccines are spreading widely on social media, researchers warn. They could undermine public health efforts to curb the pandemic.